I-HA-PRP Tube
Incazelo emfushane:
I-PRP-HA KIT iwuhlelo olusha oluchazwe kabusha emithini yobuhle, yezifo zabesifazane kanye ne-andrological ehlanganisa imiqondo yokwelapha emibili kweyodwa ngemiphumela yemvelo.
I-Osteoarthritis (OA) ingenye yemithwalo yezifo ebaluleke kakhulu emhlabeni jikelele.I-hip iyindawo yesibili evamile ye-OA ngemuva kwedolo.Iningi le-hip OA liyinhloko, nakuba lingahlotshaniswa nezinye izifo zezingane ze-hip noma izici ezithile zobungozi ezifana nokukhula kweminyaka, ukukhuluphala kanye nemidlalo enomthelela omkhulu.Iningi leziguli lizobika ukuqala okucashile kobuhlungu be-hip obunzima ngaphandle kokulimala okucacile.Ukuxilongwa kwenziwa kalula kuma-radiographs.
I-CASE VIGNETTE
Welapha umsubathi wesifazane oneminyaka engama-51 ubudala one-osteoarthritis ye-hip ethambile.Ubuza ngezinto ezingakuhlinzeki njengoba efuna ukuqhubeka nokugijima.Yikuphi kokulandelayo okungeke kuthathwe njengokwelashwa komugqa wokuqala?
A) Ukwelapha Ngomzimba
B) I-NSAIDS
C) Umjovo we-intra-articular
D) Izicathulo ezifanele
Ababhali balolu cwaningo benze ukubuyekezwa okuhlelekile kanye nokuhlaziywa kwemeta kwezifundo ezikhona ukuze kuqhathaniswe lezi zindlela ezine zokwelapha (CS, HA, PRP, NS).Izifundo ezifanele kufanele zibe yizilingo ezilawulwa ngokungahleliwe ezihlola ukusebenza kahle kwe-CS, HA, PRP kanye ne-placebo (NS) ezigulini ezine-hip OA.Ekugcineni, bafaka i-11 RCTs ehlanganisa iziguli ze-1353.Empeleni, baphethe ngokuthi awukho umehluko phakathi kwe-NS, CS, PRP ne-HA ye-hip OA ezinyangeni ezi-2, ezi-4 nezi-6.Lokhu bekuyiqiniso kukho kokubili isisindo samangqamuzana esiphansi nesiphezulu se-HA.
Lolu cwaningo bekuwukuhlaziywa kwe-meta yenethiwekhi okufake kuphela ubufakazi bezinga 1 obusiza ngempela umfundi ukuthi afinyelele iziphetho mayelana nempumelelo yokuqhathanisa.Balandele imihlahlandlela ye-Cochrane ne-PRISMA.Imikhawulo ihlanganisa (ngokulinganiselwe) usayizi wesampula omncane nokuthi abalobi abazange baqhathanise imijovo ye-IA nezinye izindlela zokuphatha okungezona ukusebenza.Futhi akubonakali ukwehlukanisa phakathi kwezigaba ezihlukene ze-hip OA lapho abaphathi, okuhlanganisa imijovo ye-IA, kungahluka kakhulu.
Lolu ucwaningo oluqinile olunikeza ubufakazi bezinga lesi-5 lokuphathwa kwe-hip OA.Akusho ukuthi i-CS, i-PRP ne-HA ayisebenzi, kunalokho bekungekho umehluko ophawulekayo uma kuqhathaniswa ne-NS ezinyangeni ezingu-2, 4 nezi-6.Imijovo ye-IA ihlala iyingxenye yokuphathwa kwe-multimodal ye-hip OA engahlinzeki.Cishe kukhona indawo yophenyo olwengeziwe lapha mayelana nezikhathi zokujova, inhlanganisela yemijovo kanye nokucabangela imiphumela yemithi ebulala izinzwa yendawo (eyaziwa nangokuthi i-chondrotoxic).
