Ishubhu ye-PRP yokuqoqwa kwegazi
Incazelo emfushane:
Imikhiqizo ethathwe ngegazi ibonise amandla ayo okuthuthukisa ukuphulukiswa nokugqugquzela ukuvuselelwa kwezicubu ezihlukahlukene futhi lo mphumela othuthukisayo ubangelwa izici zokukhula kanye namaprotheni e-bioactive ahlanganiswa futhi akhona egazini.
Ama-pathologies omgogodla ngokuvamile abonakala ngendlela yobuhlungu beqolo obukhazimula kuma-peripheries, izinzwa kanye nokulahlekelwa kwemoto.Konke lokhu ekugcineni kuthinta izinga lempilo futhi kwenyuse izinga lokugula.Ucwaningo luye lwasekela ukusetshenziswa kwe-PRP ekwelapheni ubuhlungu be-back.Ukusebenza nokuphepha kwe-PRP njengokwelashwa kwebhayoloji yezimo zomgogodla eziwohlokayo nakho kufakazelwa.Ucwaningo luhlole ukuphumelela kwe-PRP kubahlanganyeli abakhethiwe ngemva kokuqinisekisa isifo se-disc ngokusebenzisa i-imaging resonance magnetic (MRI) kanye ne-discography evuselelayo evamile.Abazobhapathizwa banikezwe ukwelashwa kwe-PRP futhi balandelelwa izinyanga eziyishumi.Imiphumela yabonisa ukuthuthukiswa okuphawulekayo kobuhlungu ngaphandle kwemiphumela emibi esobala.
I-PRP ivuselela indawo elimele futhi iqala izinqubo zokwanda, ukuqasha, nokuhlukanisa, ukuqala ukulungiswa.Ukukhishwa okulandelayo kwezici zokukhula ezifana ne-VEGF, EGF, TGF-b, ne-PDGF kunomthelela ekuthuthukiseni ubuqotho bezicubu ezilimele.Ukwakhiwa kwe-matrix yamaselula kanye ne-extracellular kusekela i-disc intervertebral ebhubhisayo, futhi ngaleyo ndlela, kunciphisa ubunzima besifo.
Enye yezindlela zokubhujiswa kwezicubu ngokweqile ukwenza kusebenze okungalawuleki kwe-cascade evuthayo kanye nokungalingani phakathi kwamahomoni avuthayo naphikisayo.Ama-chemokines nama-cytokines ngaphakathi kwama-platelet avuselela izici ze-immunological kanye nokuvuvukala kokuphulukisa, kuyilapho ama-cytokines e-anti-inflammatory ephikisana nokuqashwa ngokweqile kwama-leukocyte.Ukulawulwa okubushelelezi kwama-chemokines kuvimbela ukuvuvukala ngokweqile, okwandisa ukuphulukiswa nokunciphisa umonakalo.
Ukuwohloka kwediski kuyinqubo eyinkimbinkimbi.Kungaba ngenxa yokuguga, ukungasebenzi kahle kwe-vascular, i-apoptosis, ukunciphisa izakhi kumaseli e-disc, kanye nezici zofuzo.Imvelo ye-avascular ye-disc iphazamisa ukuphulukiswa kwezicubu.Ngaphezu kwalokho, izinguquko ezibangelwa ukuvuvukala zenzeka kokubili i-nucleus pulposus kanye ne-inner annulus fibrosus.Lokhu kubangela ukuthi amangqamuzana e-disc akhulule inani elikhulu lama-cytokines ane-pro-inflammatory akhulisa ukubhujiswa.Ukujova kwe-PRP ngqo kwi-disc ethintekile kuvumela ukuphulukiswa ukuthi kwenzeke kahle.
