Manje sesenze ngempumelelo uchungechunge lwe-plasma ecebile ye-platelet (PRP) kanye nemijovo ye-hyaluronic acid ye-OA edolweni futhi abaningi baye baba nesifo esithuthuke kakhulu kunokufaneleka (abasabela kahle kakhulu banezinguquko ezincane ze-radiological), kodwa ~ 80% baye baba nesikhathi eside futhi izimpendulo ezingcono ku-PRP noma i-viscosupplementation kunezokwelapha zangaphambili ze-intra-articulator corticosteroid.
Ukubuyekezwa okukodwa kwakamuva kanye nesilingo sakamuva kungenze ngenze lesi sibuyekezo esifushane ku-PRP kanye ne-viscosupplementation therapy yamadolo.
Ukubuyekezwa ku-Arthroscopy kuphethe i-PRP "iyindlela yokwelapha esebenzayo ye-Knee OA futhi inamandla okuholela ekukhululekeni kwezimpawu kuze kufike ezinyangeni ezingu-12".Ngaphezu kwalokho, ukwelashwa kwe-PRP ye-intra-articular "kuhlinzeka ngokukhululeka okungcono kwezimpawu ezigulini ezinezinguquko zokuqala zokuwohloka kwamadolo, futhi ukusetshenziswa kwayo kufanele kucatshangelwe ezigulini ezine-Knee OA". .
Idizayini yesilingo:
•Ingqikithi yeziguli ze-162 ezinezigaba ezihlukene ze-knee OA zahlukaniswa ngokungahleliwe zibe amaqembu amane: ngamunye wayenemijovo ye-3 ngayinye: I-3 IA amanani we-PRP, umthamo owodwa we-PRP, i-3 inj ye-HA (hyaluronic acid) noma umjovo we-saline (ukulawula) .
•Amaqembu amancane amabili: i-OA yokuqala (i-Kellgren–Lawrence ibanga 0 ngokuwohloka koqwanga noma ibanga I–III) kanye ne-OA ethuthukisiwe (i-Kellgren–Lawrence ibanga le-IV).
•Iziguli zahlolwa ngaphambi komjovo nasekulandeleni izinyanga ezingu-6 kusetshenziswa i-EuroQol visual analogue scale (EQ-VAS) kanye ne-International Knee Documentation Committee (IKDC) amaphuzu azimele.
Imiphumela:
•Kube nokuthuthukiswa okuphawulekayo kwezibalo kuzikolo ze-IKDC kanye ne-EQ-VAS kuwo wonke amaqembu okwelapha uma kuqhathaniswa neqembu lokulawula.
•Amanani amadolo eziguli eziphathwe ngemijovo emithathu ye-PRP ayengcono kakhulu kuneziguli zamanye amaqembu.Kwakungekho mehluko ophawulekayo emananini eziguli ezijovwe ngomthamo owodwa we-PRP noma we-HA.
•Emaqenjini amancane e-OA, imiphumela engcono kakhulu yomtholampilo yafinyelelwa ezigulini ezelashwa ngemijovo emithathu ye-PRP, kodwa awukho umehluko ophawulekayo emiphumeleni yomtholampilo yeziguli ezine-OA ethuthukisiwe phakathi kwamaqembu okwelapha.
Iziphetho:
1.Imiphumela yomtholampilo yalolu cwaningo iphakamisa ukwelashwa kwe-PRP ye-intra-articular ne-HA kuzo zonke izigaba ze-Knee OA.
2.Ezigulini ezine-OA yakuqala, imijovo ye-PRP eminingi (3) iwusizo ekuzuzeni imiphumela engcono yomtholampilo.
3.Ezigulini ezine-OA ethuthukisiwe, imijovo eminingi ayithuthukisi kakhulu imiphumela yeziguli kunoma yiliphi iqembu.
Isikhathi sokuthumela: Nov-07-2022