I-knee osteoarthritis iphindaphindeke kabili ekusakazekeni kusukela maphakathi nekhulu lama-20

I-Knee osteoarthritis yisifo esivame kakhulu, esikhubaza amalunga esinezimbangela ezihlala zingaqondwa kahle kodwa ngokuvamile zibangelwa ukuguga nokukhuluphala.Ukuze uthole ukuqonda nge-etiology ye-knee osteoarthritis, lolu cwaningo lulandelela izitayela zesikhathi eside kulesi sifo e-United States kusetshenziswa amasampula amakhulu ohlaka lwamathambo asukela ezikhathini zangaphambi komlando kuze kube manje.Sibonisa ukuthi i-knee osteoarthritis kade yaba khona ngamaza aphansi, kodwa kusukela maphakathi nekhulu lama-20, lesi sifo siye saphindeka kabili.Ukuhlaziya kwethu kuyaphikisana nombono wokuthi ukwanda kwakamuva kwe-knee osteoarthritis kwenzeke ngenxa nje yokuthi abantu baphila isikhathi eside futhi bavame ukukhuluphala kakhulu.Esikhundleni salokho, imiphumela yethu iqokomisa isidingo sokutadisha izici eziyingozi ezingagwemeka eziye zaba yonke indawo phakathi nengxenye yokugcina yekhulunyaka.

I-Knee osteoarthritis (OA) kukholakala ukuthi ivame kakhulu namuhla ngenxa yokwanda kwakamuva kweminyaka yokuphila kanye ne-body mass index (BMI), kodwa lokhu kucabangela akuzange kuhlolwe kusetshenziswa idatha yesikhathi eside yomlando noma yokuziphendukela kwemvelo.Sihlaziye amathrendi esikhathi eside ekwandeni kwe-OA yamadolo e-United States sisebenzisa amathambo atholakala ku-cadaver abantu abaneminyaka engu-≥50 y i-BMI yabo ekufeni yabhalwa futhi abaphila ngesikhathi sokuqala kwezimboni (1800s kuya ekuqaleni kwawo-1900s;n= 1,581) kanye nenkathi yesimanje postindustrial (ngasekupheleni 1900s kuya ekuqaleni 2000s;n= 819).I-OA yamadolo phakathi kwabantu abalinganiselwa ukuthi baneminyaka engu-≥50 ubudala nayo yahlolwa emathanjeni amathambo atholakala emivubukulweni abazingeli bangaphambi komlando nabalimi bokuqala (6000–300 BP;n= 176).I-OA yatholwa ngokusekelwe ekubeni khona kwe-eburnation (i-polish kusukela ekuthintaneni kwethambo-on-bone).Sekukonke, ukusabalala kwe-OA yamadolo kutholwe kuyi-16% phakathi kwesampula yangemva kwezimboni kodwa kuphela u-6% no-8% phakathi kwamasampula okuqala ezimboni kanye nangaphambi komlando, ngokulandelana.Ngemva kokulawula iminyaka yobudala, i-BMI, nezinye izinto eziguquguqukayo, ukwanda kwe-OA yamadolo kwakuphakeme ngokuphindwe izikhathi ezingu-2.1 (isikhawu sokuzethemba esingu-95%, 1.5–3.1) kusampula yangemva kwezimboni kunesampula yokuqala yezimboni.Imiphumela yethu ikhombisa ukuthi ukwanda kokuphila isikhathi eside kanye ne-BMI akwanele ukuchaza cishe ukuphindwa kabili kokuvama kwe-OA yamadolo okwenzeke e-United States kusukela maphakathi nekhulu lama-20.Ngakho-ke i-Knee OA igwemeka kakhulu kunalokho okuvame ukucatshangwa, kodwa ukuvimbela kuzodinga ucwaningo ngezici ezingeziwe ezizimele eziyingozi okungenzeka ukuthi zavela noma eziye zandiswa enkathini yangemva kwezimboni.